Fertility protective effects of Brillantaisia patula leaf extract against cyclophosphamide-induced ovarian damage in Wistar rats

Considered as a whole, the aqueous leaf extract of Brillantaisia patula reversed oxidative stress and inflammatory side effects of cyclophosphamide, preserving ovarian function and fertility in the rats. This may suggest its exploration as a safe agent against toxic side effects of chemotherapy and fertility-related disorders of the uterus and ovary.

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Publication Details

Journal
BMC Biotechnology
Published
2024-11-08
DOI
https://doi.org/10.1186/s12896-024-00916-8
Citations
3
Primary Topic
Reproductive Biology and Fertility
Type
article
Field-Weighted Citation Impact
1.63

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article

Fertility protective effects of Brillantaisia patula leaf extract against cyclophosphamide-induced ovarian damage in Wistar rats

Olalekan Bukunmi Ogunro, Bankole Emmanuel Ofeniforo
3 citations
BMC Biotechnology
Reproductive Biology and Fertility
1.63
article

Fertility protective effects of Brillantaisia patula leaf extract against cyclophosphamide-induced ovarian damage in Wistar rats

Olalekan Bukunmi Ogunro, Bankole Emmanuel Ofeniforo
article en
3 citations

Abstract

Considered as a whole, the aqueous leaf extract of Brillantaisia patula reversed oxidative stress and inflammatory side effects of cyclophosphamide, preserving ovarian function and fertility in the rats. This may suggest its exploration as a safe agent against toxic side effects of chemotherapy and fertility-related disorders of the uterus and ovary.

BMC BiotechnologyVol. 24(1)
University of Ibadan (NG), Oduduwa University (NG), KolaDaisi University
Directorate for Biological Sciences
Zero hunger
Openalex Percentile: Top 15%
Reproductive Biology and Fertility
1.63
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