GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma
These findings reveal a novel role of GPER1 signaling in regulating macrophage proliferation and function in HCC tumors and may offer a potential strategy for designing therapies based on understanding sex-related disparities of patients.
Authors
- Hao Zou (ORCID: https://orcid.org/0000-0001-9140-418X)
- Zhijie Huang (ORCID: https://orcid.org/0000-0002-7312-4982)
- Yulan Weng (ORCID: https://orcid.org/0000-0003-1089-2252)
- Weibai Chen
- Xing-Juan Yu (ORCID: https://orcid.org/0009-0009-3667-1969)
- Yongchun Wang (ORCID: https://orcid.org/0000-0002-8297-2908)
- Yanyan Yang (ORCID: https://orcid.org/0000-0001-7551-6376)
- Jing Xu (ORCID: https://orcid.org/0000-0002-4713-2807)
- Limin Zheng (ORCID: https://orcid.org/0000-0002-8281-1450)
- Zhixiong Li (ORCID: https://orcid.org/0009-0008-0409-9331)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-08
- DOI
- https://doi.org/10.3389/fimmu.2024.1481972
- Citations
- 4
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 2.20