An evaluation of genetic predisposition to congenital anomalies and pediatric cancer supports KAT6B as a novel neuroblastoma susceptibility gene

This study demonstrates a molecular diagnostic yield of 23.4% in participants with both anomalies and cancer. Additionally, the findings further implicate the role of <i>KAT6B</i> as a novel neuroblastoma predisposition gene.

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Publication Details

Journal
Genetics in Medicine Open
Published
2024-11-08
DOI
https://doi.org/10.1016/j.gimo.2024.101901
Citations
2
Primary Topic
Neuroblastoma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.74

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article

An evaluation of genetic predisposition to congenital anomalies and pediatric cancer supports KAT6B as a novel neuroblastoma susceptibility gene

Jennifer E. Posey, Michael E. Scheurer, Pamela Mishra, Xi Yao et al.
2 citations
Genetics in Medicine Open
Neuroblastoma Research and Treatments
0.74
article

An evaluation of genetic predisposition to congenital anomalies and pediatric cancer supports KAT6B as a novel neuroblastoma susceptibility gene

Jennifer E. Posey, Michael E. Scheurer, Pamela Mishra, Xi Yao, Danielle Mitchell, Sharon E. Plon, Marie‐Claude Gingras, Sravya Bhamidipati, Hyunjung Gu, HarshaVardhan Doddapaneni, Saumya D. Sisoudiya, Philip J. Lupo, Shalini N. Jhangiani, Olga A. Taylor, Jeremy M. Schraw, Aniko Sabo, Shannon Dugan‐Perez, He Li, Yifan Wu, Donna M. Muzny, Chad Huff, Richard A. Gibbs
article en
2 citations

Abstract

This study demonstrates a molecular diagnostic yield of 23.4% in participants with both anomalies and cancer. Additionally, the findings further implicate the role of <i>KAT6B</i> as a novel neuroblastoma predisposition gene.

Genetics in Medicine OpenVol. 3
The University of Texas MD Anderson Cancer Center (US), Baylor College of Medicine (US), Texas Children's Hospital (US), Children's Cancer Center (US), Baylor Genetics (US)
Cancer Prevention and Research Institute of Texas, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 26%
Neuroblastoma Research and Treatments
0.74
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