Non-dioxin-like polychlorinated biphenyls (NDL-PCBs) dietary exposure is associated with an increased risk of type 2 diabetes in the European prospective investigation into cancer and nutrition (EPIC) cohort
Results obtained in this large European prospective study indicate a positive and linear association between dietary intake of NDL-PCBs and risk of T2DM. This association remained consistent across various stratified and sensitivity analyses. Further studies are warranted to better understand the biological mechanisms underlying this association.
Authors
- Alicia K. Heath (ORCID: https://orcid.org/0000-0001-6517-1300)
- Pauline Frénoy (ORCID: https://orcid.org/0000-0002-7435-5125)
- Claudia Vener (ORCID: https://orcid.org/0000-0001-7351-8634)
- Matthias Bernd Schulze (ORCID: https://orcid.org/0000-0002-0830-5277)
- Fulvio Ricceri (ORCID: https://orcid.org/0000-0001-8749-9737)
- Paolo Chiodini (ORCID: https://orcid.org/0000-0003-0139-2264)
- Thibault Fiolet (ORCID: https://orcid.org/0000-0002-0292-9863)
- Chloé Marques (ORCID: https://orcid.org/0000-0003-3203-7310)
- Giovanna Masala (ORCID: https://orcid.org/0000-0002-5758-9069)
- Geneviève Nicolas (ORCID: https://orcid.org/0000-0001-7871-7149)
- Franziska Jannasch (ORCID: https://orcid.org/0000-0003-3478-4758)
- Francesca Romana Mancini (ORCID: https://orcid.org/0000-0003-2297-3869)
- Inge Huybrechts (ORCID: https://orcid.org/0000-0003-3838-855X)
- Sandra M. Colorado‐Yohar (ORCID: https://orcid.org/0000-0002-6700-0780)
- Conchi Moreno‐Iribas (ORCID: https://orcid.org/0000-0001-6537-0131)
- Christina C. Dahm (ORCID: https://orcid.org/0000-0003-0481-2893)
- Elisabete Weiderpass (ORCID: https://orcid.org/0000-0003-2237-0128)
- Paolo Vineis (ORCID: https://orcid.org/0000-0001-8935-4566)
- Gianluca Severi (ORCID: https://orcid.org/0000-0001-7157-419X)
- Keren Papier (ORCID: https://orcid.org/0000-0002-4102-6835)
- Jie Zhang (ORCID: https://orcid.org/0000-0002-1985-5485)
- Xuan Ren (ORCID: https://orcid.org/0009-0006-9589-3412)
Institutions
- European Food Safety Authority (IT)
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- University of Campania "Luigi Vanvitelli" (IT)
- Aarhus University (DK)
- Université Paris-Saclay (FR)
- Prevention Institute (US)
- Institut Gustave Roussy (FR)
- Public Health England (GB)
- University of Oxford (GB)
- Instituto de Salud Pública de Navarra (ES)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Deutsches Diabetes-Zentrum e.V. (DE)
- Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- German Institute of Human Nutrition (DE)
- Centre international de recherche sur le cancer (FR)
- Heinrich Heine University Düsseldorf (DE)
- Imperial College London (GB)
- University of Turin (IT)
Publication Details
- Journal
- Diabetes & Metabolism
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.diabet.2024.101587
- Citations
- 1
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- World Health Organization
- Deutsches Krebsforschungszentrum
- Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation
- European Food Safety Authority
- Cancer Research UK
- National Institute for Health and Care Research
- Imperial College London
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Bundesministerium für Bildung und Forschung
- Cancerfonden
- Ligue Contre le Cancer
- Vetenskapsrådet
- Associazione Italiana per la Ricerca sul Cancro
- Deutsche Krebshilfe
- Associazione Iblea per la Ricerca Epidemiologica
- Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail
- Institut Gustave-Roussy
- Mutuelle Générale de l'Education Nationale
- Medical Research Council
- World Cancer Research Fund
- Instituto de Salud Carlos III
- NIHR Imperial Biomedical Research Centre
- School of Public Health, Imperial College London