Transient receptor potential channel 6 knockout ameliorates hepatic fibrosis by inhibiting the activation and proliferation of hepatic stellate cells
These observations suggested that TRPC6 contribute to LX-2 cell activation and hepatic fibrosis, and downregulation of TRPC6 may become a therapeutic strategy for the treatment of hepatic fibrosis in the future.
Authors
- Wei‐Yi Cheng (ORCID: https://orcid.org/0000-0002-7588-298X)
- Yanhong Liao (ORCID: https://orcid.org/0000-0001-6308-3120)
- Xixi Zeng (ORCID: https://orcid.org/0000-0002-0114-5936)
Institutions
- Union Hospital (HK)
- Wuhan University (CN)
- Wuhan Union Hospital (CN)
- Renmin Hospital of Wuhan University (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1111/jgh.16802
- Citations
- 2
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- National Natural Science Foundation of China