Novel Scoring System for Ranking Hematopoietic Stem Cell Transplantation
This study suggests that HLA mismatches that do not alter peptide binding or orientation (Peptide Score = 0) could expand the number of permissive HLA mismatches. Further investigation is needed to confirm this observation and to explore alternative scoring systems for ranking HLA mismatched donors.
Authors
- Esteban Arrieta‐Bolaños (ORCID: https://orcid.org/0000-0002-3696-5803)
- Stephanie J. Lee (ORCID: https://orcid.org/0000-0003-2600-6390)
- Martin Maiers (ORCID: https://orcid.org/0000-0002-0198-2064)
- Brian C. Betts (ORCID: https://orcid.org/0000-0001-7643-2422)
- Jennifer N. Saultz (ORCID: https://orcid.org/0000-0003-0024-9466)
- Yung‐Tsi Bolon (ORCID: https://orcid.org/0000-0001-9414-6120)
- Michelle Kuxhausen
- Stephen R. Spellman (ORCID: https://orcid.org/0000-0002-7271-8252)
- Shahinaz M. Gadalla (ORCID: https://orcid.org/0000-0002-3255-8143)
- Lee Ann Baxter‐Lowe (ORCID: https://orcid.org/0000-0002-6706-0273)
- Tao Wang (ORCID: https://orcid.org/0000-0002-2596-6843)
Institutions
- University of Southern California (US)
- Roswell Park Comprehensive Cancer Center (US)
- National Marrow Donor Program (US)
- Children's Hospital of Los Angeles (US)
- Oregon Health & Science University (US)
- Medical College of Wisconsin (US)
- Fred Hutch Cancer Center (US)
- Essen University Hospital (DE)
- Cancer Genetics (United States) (US)
- Division of Cancer Epidemiology and Genetics
Publication Details
- Journal
- Clinical Transplantation
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1111/ctr.15478
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gateway for Cancer Research
- Amgen
- Bristol-Myers Squibb
- Pfizer
- Astellas Pharma US
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Gilead Sciences
- Alexion Pharmaceuticals
- AbbVie
- HistoGenetics
- Novartis Pharmaceuticals Corporation
- CSL Behring
- Medical College of Wisconsin
- Actinium Pharmaceuticals
- Vertex Pharmaceuticals
- Jazz Pharmaceuticals
- Mallinckrodt Pharmaceuticals
- Atara Biotherapeutics
- CareDx
- bluebird bio
- Adaptive Biotechnologies
- BeiGene
- Incyte
- Pediatric Transplantation and Cellular Therapy Consortium
- Omeros Corporation
- Seagen
- Kiadis Pharma
- Kyowa Hakko Kirin
- Astellas Pharma
- Swedish Orphan Biovitrum
- MorphoSys
- Medac
- Health Resources and Services Administration
- U.S. Public Health Service
- Takeda Oncology
- Pharmacyclics
- Legend Biotech
- National Heart, Lung, and Blood Institute
- Office of Naval Research
- National Cancer Institute
- National Institute of Allergy and Infectious Diseases