Associations of schizophrenia with arrhythmic disorders and electrocardiogram traits: genetic exploration of population samples
Despite little evidence for global genetic correlation, specific genomic regions and biological pathways emerged that are important for both schizophrenia and arrhythmia. The putative causal effect of liability to schizophrenia on Brugada syndrome warrants increased cardiac monitoring and early medical intervention in people with schizophrenia.
Authors
- Dirk J. A. Smit (ORCID: https://orcid.org/0000-0001-8301-8860)
- Jentien M. Vermeulen (ORCID: https://orcid.org/0000-0002-6245-6498)
- Damiaan Denys (ORCID: https://orcid.org/0000-0002-3191-3844)
- Connie R. Bezzina (ORCID: https://orcid.org/0000-0002-0633-3514)
- Jacob Bergstedt (ORCID: https://orcid.org/0000-0002-9279-6936)
- Rafik Tadros (ORCID: https://orcid.org/0000-0002-1472-0258)
- Julien Barc (ORCID: https://orcid.org/0000-0003-4106-5946)
- Rada R Veeneman (ORCID: https://orcid.org/0000-0003-3471-1049)
- Jorien L. Treur (ORCID: https://orcid.org/0000-0003-4370-3390)
- Joëlle A. Pasman (ORCID: https://orcid.org/0000-0001-7558-0482)
- Anaïs B Thijssen (ORCID: https://orcid.org/0000-0001-6782-3608)
- Karin J. H. Verweij (ORCID: https://orcid.org/0000-0001-9868-7821)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Montreal Heart Institute (CA)
- Karolinska Institutet (SE)
- Amsterdam Neuroscience (NL)
- Institut du Thorax (FR)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
- Nantes Université (FR)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1192/bjp.2024.165
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- Stichting Volksbond Rotterdam
- European Commission
- Fondation Leducq
- Canada Research Chairs