Herbo-vitamin medicine Livogrit Vital ameliorates isoniazid induced liver injury (IILI) in human liver (HepG2) cells by decreasing isoniazid accumulation and oxidative stress driven hepatotoxicity
Treatment of hepatic cells with the herbo-vitamin medicine, Livogrit Vital, regulates IILI by modulation of oxidative and ER stress, apoptosis, and bioaccumulation of isoniazid and hydrazine. Collectively, Livogrit Vital could well be explored as an adjuvant hepatoprotective agent alongwith anti-TB medicines.
Authors
- Rishabh Dev (ORCID: https://orcid.org/0000-0002-7878-6934)
- Meenu Tomer
- Vivek Gohel (ORCID: https://orcid.org/0000-0002-4530-9971)
- Anurag Varshney (ORCID: https://orcid.org/0000-0001-8509-0882)
- Acharya Balkrishna (ORCID: https://orcid.org/0000-0003-4749-6317)
Institutions
- Jawaharlal Nehru University (IN)
- Patanjali Research Foundation (IN)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s12906-024-04685-x
- Citations
- 4
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 1.87