Impact of metabolism-related markers on outcomes in ovarian cancer patients: Findings of the MITO16A/MaNGO-OV2 trial
These results indicate marked heterogeneity of expression of metabolism-associated markers in ovarian cancer; however, there was a lack of association with clinical benefit after chemotherapy/anti-vascular endothelial growth factor treatment. Notwithstanding the lack of prognostic value, knowledge of the pattern of expression of these biomarkers in tumors can be useful for patient stratification purposes when new drugs targeting these metabolic pathways will be tested.
Authors
- Alessandra Bologna (ORCID: https://orcid.org/0000-0001-7901-5499)
- Simona Signoriello (ORCID: https://orcid.org/0000-0001-5194-3269)
- Saverio Cinieri (ORCID: https://orcid.org/0000-0002-5555-0814)
- Grazia Artioli
- Federica Perrone (ORCID: https://orcid.org/0000-0003-4406-8245)
- Ilaria Piga (ORCID: https://orcid.org/0000-0002-4948-0709)
- Annamaria Ferrero (ORCID: https://orcid.org/0000-0002-2909-3699)
- Laura Arenare (ORCID: https://orcid.org/0000-0001-7100-4517)
- Stefano Indraccolo (ORCID: https://orcid.org/0000-0002-4810-7136)
- Carmela Pisano (ORCID: https://orcid.org/0000-0003-4577-6534)
- Fabrizio Ferrarini (ORCID: https://orcid.org/0000-0002-9492-2123)
- Daniela Califano (ORCID: https://orcid.org/0000-0001-6945-3209)
- Germana Tognon (ORCID: https://orcid.org/0000-0003-3935-4992)
- Carolina Bottoni (ORCID: https://orcid.org/0000-0003-2084-8263)
- Vittorio Simeon (ORCID: https://orcid.org/0000-0003-2387-4125)
- Paolo Chiodini (ORCID: https://orcid.org/0000-0003-0139-2264)
- Giosuè Scognamiglio (ORCID: https://orcid.org/0000-0003-4376-111X)
- Eliana Bignotti (ORCID: https://orcid.org/0000-0001-6380-6181)
- Anna Spina (ORCID: https://orcid.org/0000-0002-4726-9299)
- Andrea Boscolo Bragadin (ORCID: https://orcid.org/0000-0001-9614-0814)
- Giovanni Esposito (ORCID: https://orcid.org/0000-0001-7960-5253)
- Daniela Russo (ORCID: https://orcid.org/0000-0001-9471-1935)
- Sandro Pignata (ORCID: https://orcid.org/0000-0002-8836-2633)
- Vanda Salutari (ORCID: https://orcid.org/0000-0002-9420-7146)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Padua (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Agostino Gemelli University Polyclinic (IT)
- Azienda Sanitaria Unità Locale di Reggio Emilia (IT)
- AULSS 2 Marca Trevigiana (IT)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Ospedale A. Perrino (IT)
- Istituto Oncologico Veneto (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- A. O. Ordine Mauriziano di Torino (IT)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- The International Journal of Biological Markers
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1177/03936155241296164
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- Ministero della Salute
- Associazione Italiana per la Ricerca sul Cancro