Tricuspid Valve Reconstruction in Patients with Right Heart Decompensation Due to Severe Tricuspid Regurgitation on LVAD Support

<b>Background/Objectives</b>: Right ventricular (RV) dysfunction after left ventricular assist device (LVAD) implantation is associated with reduced survival and affects duration of hospitalization. Some patients with RV dysfunction on LVAD have significant tricuspid valve regurgitation (TR) with concomitant signs of RV failure. In these cases, tricuspid valve repair (TVR) may minimize clinical signs of RV failure. <b>Methods</b>: We report on two patients (one female, one male) developing significant TR receiving TVR through a right thoracotomy on LVAD support. <b>Results</b>: The time between LVAD implantation and TVR was 4 months and 50 months, respectively. The female patient could be discharged from hospital without TR and any signs of RV dysfunction. The male patient died 13 days later due to septic shock following mesenteric ischemia. At this time, echocardiography showed a competent tricuspid valve. <b>Conclusions</b>: In conclusion, these results provide insight into the clinical judgment of when TVR should be attempted. They suggest whether TVR may be a strategy to avoid hospitalization, minimize the clinical signs of RV insufficiency and improve quality of life in patients on LVAD support with severe TR and clinical signs of right heart dysfunction.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2024-11-08
DOI
https://doi.org/10.3390/jcm13226705
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Tricuspid Valve Reconstruction in Patients with Right Heart Decompensation Due to Severe Tricuspid Regurgitation on LVAD Support

Henryk Welp, Jürgen Sindermann, Mirela Scherer
Journal of Clinical Medicine
Mechanical Circulatory Support Devices
article

Tricuspid Valve Reconstruction in Patients with Right Heart Decompensation Due to Severe Tricuspid Regurgitation on LVAD Support

Henryk Welp, Jürgen Sindermann, Mirela Scherer
article en

Abstract

<b>Background/Objectives</b>: Right ventricular (RV) dysfunction after left ventricular assist device (LVAD) implantation is associated with reduced survival and affects duration of hospitalization. Some patients with RV dysfunction on LVAD have significant tricuspid valve regurgitation (TR) with concomitant signs of RV failure. In these cases, tricuspid valve repair (TVR) may minimize clinical signs of RV failure. <b>Methods</b>: We report on two patients (one female, one male) developing significant TR receiving TVR through a right thoracotomy on LVAD support. <b>Results</b>: The time between LVAD implantation and TVR was 4 months and 50 months, respectively. The female patient could be discharged from hospital without TR and any signs of RV dysfunction. The male patient died 13 days later due to septic shock following mesenteric ischemia. At this time, echocardiography showed a competent tricuspid valve. <b>Conclusions</b>: In conclusion, these results provide insight into the clinical judgment of when TVR should be attempted. They suggest whether TVR may be a strategy to avoid hospitalization, minimize the clinical signs of RV insufficiency and improve quality of life in patients on LVAD support with severe TR and clinical signs of right heart dysfunction.

Journal of Clinical MedicineVol. 13(22)
University Hospital Münster (DE)
Good health and well-being
Openalex Percentile: Top 82%
Mechanical Circulatory Support Devices
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