Influence of TMPRSS6 genotype on iron status parameters in stable COPD patients
Iron status parameters do not differ between WT and HH groups of stable COPD patients. Statistical but not clinical difference in EPO levels was observed in a subgroup of patients. In addition to promoting erythropoiesis, EPO may regulate hepcidin levels and thus influence the development of iron deficiency and/or anaemia. Also, EPO's direct effect on immune cells and down-regulation of inflammatory reactions should be considered in this context.
Authors
- Marko Trtica (ORCID: https://orcid.org/0000-0003-4357-6141)
- Jelena Martinović (ORCID: https://orcid.org/0000-0001-8641-1051)
- Vesna Dopuđa-Pantić
- Snežana Ž. Jovičić (ORCID: https://orcid.org/0000-0002-6878-8645)
- Branislava Milenković (ORCID: https://orcid.org/0000-0002-0767-6869)
- Ivana V. Novaković (ORCID: https://orcid.org/0000-0003-0202-0673)
- Violeta Dopsaj (ORCID: https://orcid.org/0000-0001-8310-6254)
- Sanja Dimić-Janjić (ORCID: https://orcid.org/0000-0001-9989-3862)
- Jelena Janković (ORCID: https://orcid.org/0000-0001-8529-8624)
Institutions
- Santen (Japan) (JP)
- University of Belgrade (RS)
- Kliničko Bolnički Centar Zvezdara (RS)
- Univerzitetski Klinički Centar Srbije (RS)
Publication Details
- Journal
- Journal of Medical Biochemistry
- Published
- 2024-11-08
- DOI
- https://doi.org/10.5937/jomb0-52996
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00