Determining doses for backfill cohorts based on patient-reported outcome
The Backfill-QoL design enables continuous monitoring of safety, efficacy and QoL outcomes, and the recommended phase II dose (RP2D) can be identified in a more patient-centered perspective.
Authors
- Xin Chen (ORCID: https://orcid.org/0000-0003-4418-0480)
- Bosheng Li (ORCID: https://orcid.org/0000-0002-1816-7007)
- Fangrong Yan (ORCID: https://orcid.org/0000-0003-3347-5021)
- Jingyi Zhang (ORCID: https://orcid.org/0009-0001-2543-4310)
Institutions
- China Pharmaceutical University (CN)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s12874-024-02398-w
- Citations
- 1
- Primary Topic
- Radiation Dose and Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- National Natural Science Foundation of China
- Fundamental Research Funds for the Central Universities