The causal relationship between immune cells and hepatocellular carcinoma: a Mendelian randomization (MR)
Our MR analysis of the role of immune cells and HCC provides a framework for knowledge of circulating immune status. Systematic assays of infiltrating immune cells in HCC can help dissect the immune status of HCC, assess the current use of checkpoint blockers, and most importantly, aid in the development of innovative immunotherapies. Further research is necessary to validate these findings and explore the underlying mechanisms that influence the immune response to HCC.
Authors
- Syphanna Sou
- Yangfeng Zhang (ORCID: https://orcid.org/0000-0002-4993-2808)
- Changqian Wang (ORCID: https://orcid.org/0000-0002-7611-7761)
- Duanyu Wang
- Minghao Yin (ORCID: https://orcid.org/0000-0002-6226-2394)
- Chongyang Zheng (ORCID: https://orcid.org/0009-0004-5396-0029)
- Qianzi Kou
- Pengkhun Nov (ORCID: https://orcid.org/0000-0002-7016-8285)
- Xiang Liu (ORCID: https://orcid.org/0000-0003-2556-3419)
- Kunpeng Du (ORCID: https://orcid.org/0000-0002-0684-7291)
- Peizan Ni (ORCID: https://orcid.org/0000-0002-8010-1375)
- Socheat Touch
- Lilin Li (ORCID: https://orcid.org/0000-0001-7559-1018)
- Samnang Kouy
- Jiqiang Li (ORCID: https://orcid.org/0000-0002-0962-9118)
- Wen Fu
- Virak Vicheth (ORCID: https://orcid.org/0009-0003-5562-8620)
- Arzoo Prasai
- Wandan Li
Institutions
- Zhujiang Hospital (CN)
- Hezhou University (CN)
Publication Details
- Journal
- ecancermedicalscience
- Published
- 2024-11-08
- DOI
- https://doi.org/10.3332/ecancer.2024.1794
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Natural Science Foundation of Guangdong Province