Elovanoids, a Novel Class of Lipid Mediators, Are Neuroprotective in a Traumatic Brain Injury Model in Rats
We have demonstrated that both ELV-IN and ELV-IV administration offer high-grade neuroprotection that can be selectively supplied to the brain. This discovery may lead to innovative therapeutic targets for secondary injury cascade prevention following TBI.
Authors
- Bokkyoo Jun
- Larissa Khoutorova
- Pranab K. Mukherjee (ORCID: https://orcid.org/0000-0003-0244-6068)
- André Obenaus
- Nicolás G. Bazán (ORCID: https://orcid.org/0000-0002-9243-5444)
- Ludmila Belayev (ORCID: https://orcid.org/0000-0001-8687-9340)
- Rostyslav Semikov (ORCID: https://orcid.org/0000-0002-1013-2395)
Institutions
- University of California, Riverside (US)
- Audubon Nature Institute (US)
- Louisiana State University Health Sciences Center New Orleans (US)
Publication Details
- Journal
- Biomedicines
- Published
- 2024-11-08
- DOI
- https://doi.org/10.3390/biomedicines12112555
- Citations
- 2
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.59