Plasma neurofilament analysis in VITALITY-ALS
In this large longitudinal study, baseline NfL concentration correlated with multiple markers of disease progression. The findings suggest Nfs show promise primarily as prognostic markers for pALS, particularly for those with rapid disease progression.
Authors
- Stacy A. Rudnicki (ORCID: https://orcid.org/0000-0002-3499-5208)
- Jeremy M. Shefner (ORCID: https://orcid.org/0000-0001-5067-5602)
- Tyrell Simkins (ORCID: https://orcid.org/0000-0002-6063-174X)
- Jenny Wei (ORCID: https://orcid.org/0009-0000-5828-5705)
- Robert Bowser (ORCID: https://orcid.org/0000-0001-5404-7259)
- Stuart Kupfer (ORCID: https://orcid.org/0000-0002-5469-1287)
- Lisa Meng (ORCID: https://orcid.org/0000-0003-0229-1131)
- Fady I. Malik
Institutions
- Creighton University (US)
- Barrow Neurological Institute (US)
- University of Arizona (US)
- Cytokinetics (United States) (US)
Publication Details
- Journal
- Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1080/21678421.2024.2423707
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- ALS Association
- Cytokinetics