Association analysis of gut microbiota with LDL-C metabolism and microbial pathogenicity in colorectal cancer patients
The intestinal microbiota in CRC patients influences the LDL-C metabolic status. With elevated LDL-C levels, gut microbiota can regulate the function of immune cells and gene expression within the tumor microenvironment, affecting cancer-related pathways and promoting CRC progression. LDL-C and its associated gut microbiota could provide non-invasive markers for clinical evaluation and treatment of CRC patients.
Authors
- Chenyan Long (ORCID: https://orcid.org/0000-0003-0468-8415)
- Weizhong Tang (ORCID: https://orcid.org/0000-0003-0877-8557)
- Mingjian Qin
- Xianwei Mo (ORCID: https://orcid.org/0000-0002-4245-2836)
- Fuhai He (ORCID: https://orcid.org/0000-0002-1780-9389)
- Yongzhi Wu (ORCID: https://orcid.org/0000-0002-6661-8888)
- Jungang Liu
- Chuanbin Chen (ORCID: https://orcid.org/0000-0003-2616-0654)
- Zigui Huang (ORCID: https://orcid.org/0009-0003-4438-0885)
- Binzhe Tang
- Yongqi Huang (ORCID: https://orcid.org/0009-0006-5607-8140)
- Zhen Wang (ORCID: https://orcid.org/0000-0002-8282-9781)
- Xiaoliang Huang (ORCID: https://orcid.org/0000-0001-7979-7398)
Institutions
- Guangxi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s12944-024-02333-4
- Citations
- 10
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- China Postdoctoral Science Foundation
- Natural Science Foundation of Guangxi Province
- Middle-aged and Young Teachers' Basic Ability Promotion Project of Guangxi
- Youth Science Foundation of Guangxi Medical University