Study of Molecular Markers in Glioma and Their Association with Clinicopathological Features

Molecular characterization of glioma is an important step in modern glioma diagnostics and immunohistochemistry can play an important role. IDH-1 mutation is commonly observed in adults, frontal lobe location, patients presenting with seizures, and WHO grade 2 tumors with the highest frequencies in oligodendrogliomas. ATRX and p53 can be used as surrogate markers for tumors of astrocytic lineage.

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Publication Details

Journal
Annals of African Medicine
Published
2024-11-08
DOI
https://doi.org/10.4103/aam.aam_127_23
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Study of Molecular Markers in Glioma and Their Association with Clinicopathological Features

Sarita Agrawal, Anurag Singh, Awadhesh Kumar Jaiswal, Alka Singh et al.
Annals of African Medicine
Circular RNAs in diseases
article

Study of Molecular Markers in Glioma and Their Association with Clinicopathological Features

Sarita Agrawal, Anurag Singh, Awadhesh Kumar Jaiswal, Alka Singh, Sushila Jaiswal
article en

Abstract

Molecular characterization of glioma is an important step in modern glioma diagnostics and immunohistochemistry can play an important role. IDH-1 mutation is commonly observed in adults, frontal lobe location, patients presenting with seizures, and WHO grade 2 tumors with the highest frequencies in oligodendrogliomas. ATRX and p53 can be used as surrogate markers for tumors of astrocytic lineage.

Annals of African MedicineVol. 24(1)
Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 82%
Circular RNAs in diseases
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