Determining optimal clinical target volume margins based on microscopic extracapsular extension of metastatic nodes in patients with non-small-cell lung cancer after chemotherapy or chemotherapy combined with immunotherapy
The existing CTV delineation standards may increase the radiation toxicity of patients. We believe that different CTV margins should be used for LN in patients with NSCLC receiving different treatments. To ensure 95% coverage of ECE, the gross tumor volume of untreated, chemotherapy-treated, and chemotherapy combined with immunotherapy-treated patients should be expanded by 3.00, 2.30, and 1.40 mm, respectively, to obtain the CTV.
Authors
- Jiaran Li (ORCID: https://orcid.org/0009-0002-9910-1591)
- Li Li (ORCID: https://orcid.org/0000-0003-4802-8689)
- Yujiao Zhang (ORCID: https://orcid.org/0000-0002-8820-1602)
- Fen Zhao (ORCID: https://orcid.org/0000-0001-5643-4260)
- Shuanghu Yuan
- Xiao Song (ORCID: https://orcid.org/0000-0002-7023-6778)
Institutions
- University of Science and Technology of China (CN)
- Shandong Tumor Hospital (CN)
- Rongcheng City People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s12885-024-13135-3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China