Neuro-Behçet leading to coma: A case report

Neuro-Behçet disease is often difficult to diagnose due to its complex and severe clinical presentation. This article reports the case of a 35-year-old female patient with a history of Behçet's disease, admitted for a deep coma. Brain MRI performed upon admission revealed extended lesions in the basal ganglia, thalami, and midbrain, along with leptomeningeal contrast enhancement in the temporal region, suggesting meningoencephalitis compatible with parenchymal involvement of neuro-Behçet's disease. Following a comprehensive negative evaluation for infectious and malignant causes, combined with the patient's medical history, a diagnosis of neuro-Behçet disease was established.