PM2.5 Promotes Macrophage-Mediated Inflammatory Response Through Airway Epithelial Cell-Derived Exosomal miR-155-5p

PM2.5 promotes Mφ inflammation by upregulating miRNA-155-5P in exosomes obtained from BEAS-2B cells through miR-155-5P/SOCS1/NF-κB pathway. Exosomal miRNAs mediate cellular communication between BEAS-2B cells and Mφ, which may be a new mechanism of PM2.5-stimulated pulmonary inflammatory response.

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Publication Details

Journal
Journal of Inflammation Research
Published
2024-11-01
DOI
https://doi.org/10.2147/jir.s482509
Citations
12
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
3.78

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article

PM2.5 Promotes Macrophage-Mediated Inflammatory Response Through Airway Epithelial Cell-Derived Exosomal miR-155-5p

Hui Xu, Xin Li, Ping Huang, Xiaoju Liu et al.
12 citations
Journal of Inflammation Research
Air Quality and Health Impacts
3.78
article

PM2.5 Promotes Macrophage-Mediated Inflammatory Response Through Airway Epithelial Cell-Derived Exosomal miR-155-5p

Hui Xu, Xin Li, Ping Huang, Xiaoju Liu, Kai Liu
article en
12 citations

Abstract

PM2.5 promotes Mφ inflammation by upregulating miRNA-155-5P in exosomes obtained from BEAS-2B cells through miR-155-5P/SOCS1/NF-κB pathway. Exosomal miRNAs mediate cellular communication between BEAS-2B cells and Mφ, which may be a new mechanism of PM2.5-stimulated pulmonary inflammatory response.

Journal of Inflammation ResearchVol. Volume 17
First Hospital of Lanzhou University (CN), Lanzhou University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 6%
Air Quality and Health Impacts
3.78
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PM2.5 Promotes Macrophage-Mediated Inflammatory Response Through Airway Epithelial Cell-Derived Exosomal miR-155-5p — Hui Xu, Xin Li, et al. · Journal of Inflammation Research (2024) | TGRS Research Map | TGRS