STEM CELL APPROACHES IN ORGAN REGENERATION AND REPAIR

Recent advances in stem cell research have provided new hope for treating a variety of diseases and conditions that currently have no effective cure. Stem cells have the unique ability to differentiate into various cell types, enabling them to support tissue growth and replace damaged or specialized cells throughout the lifespan. Among the most promising types of stem cells are mesenchymal stem cells (MSCs), which are easily harvested from adipose tissue and can be cultured and expanded in the lab. Due to their versatility, MSCs have become a focal point in tissue regeneration and have been widely used in animal studies and clinical trials involving humans. This review aims to summarize the current understanding of MSCs, focusing on the various types of stem cells isolated from different animal models such as horses, pigs, goats, dogs, rabbits, cats, rats, and mice. Given the growing interest in MSCs, we will also discuss their applications in veterinary and regenerative medicine. Current research highlights the potential of MSCs in treating conditions like heart failure, wound healing, and tooth regeneration, demonstrating their broad therapeutic potential. KEYWORDS: Mesenchymal stem cells (MSCs), animal models, cell-based therapy, regenerative medicine