Longitudinal stability of molecular endotypes of knee osteoarthritis patients
Our study showed for the first time that more than half of KOA participants exhibited a longitudinally stable endotype, highlighting the applicability of biomarker-based endotyping in a clinical trial setting.
Authors
- Anne‐Christine Bay‐Jensen (ORCID: https://orcid.org/0000-0001-7952-9297)
- André Struglics (ORCID: https://orcid.org/0000-0003-4289-1393)
- C. Ladel (ORCID: https://orcid.org/0000-0001-8657-6219)
- Jaume Bacardit (ORCID: https://orcid.org/0000-0002-2692-7205)
- Yves Henrotin (ORCID: https://orcid.org/0000-0003-1073-449X)
- Ali Mobasheri (ORCID: https://orcid.org/0000-0001-6261-1286)
- Peder Frederiksen
- Cecilie L. Bager (ORCID: https://orcid.org/0000-0003-2430-9777)
- Monica T. Hannani (ORCID: https://orcid.org/0000-0002-4123-6832)
- Jonathan Larkin (ORCID: https://orcid.org/0000-0002-1202-9287)
- Mélanie Uebelhoer (ORCID: https://orcid.org/0000-0002-7911-3205)
- Alfred Gellhorn (ORCID: https://orcid.org/0000-0002-6020-780X)
- Asger Reinstrup Bihlet (ORCID: https://orcid.org/0000-0002-6944-1731)
- M.A. Karsdal (ORCID: https://orcid.org/0000-0001-5026-8740)
- Christian S. Thudium (ORCID: https://orcid.org/0000-0002-0202-1417)
- Francis Bérenbaum (ORCID: https://orcid.org/0000-0001-8252-7815)
- Zofia Lisowska-Petersen
- I.K. Haugen (ORCID: https://orcid.org/0000-0001-7810-2216)
- F.J. Blanco (ORCID: https://orcid.org/0000-0002-0964-9215)
- M. Kloppenburg (ORCID: https://orcid.org/0000-0002-9294-2307)
Institutions
- Inserm (FR)
- University of Liège (BE)
- Lund University (SE)
- Oulu University Hospital (FI)
- Leiden University Medical Center (NL)
- NBCUniversal (United States) (US)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- GlaxoSmithKline (United States) (US)
- Diakonhjemmet Hospital (NO)
- Christophorus Kliniken (DE)
- Centre de Recherche Saint-Antoine (FR)
- Nordic Bioscience (Denmark) (DK)
- Instituto de Investigación Biomédica de A Coruña (ES)
- Artistic Realization Technologies (US)
- Newcastle University (GB)
- Technical University of Denmark (DK)
- University of Oulu (FI)
Publication Details
- Journal
- Osteoarthritis and Cartilage
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1016/j.joca.2024.11.002
- Citations
- 7
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.29
Funders
- Amgen
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- World Health Organization
- Gilead Sciences
- Celgene
- CSL Behring
- Merck KGaA
- Kiniksa Pharmaceuticals
- Dutch Arthritis Society
- Boehringer Ingelheim España
- Pacira BioSciences
- Arthritis Society
- Université de Liège
- Servier
- Novartis Farmacéutica
- Sun Pharma
- UCB US
- Cilag