Single-Cell Profiling of Tubular Epithelial Cells in Adaptive State in the Urine Sediment of Patients With Early and Advanced Diabetic Kidney Disease
Urine is an underestimated source of aTECs providing us noninvasive manner to interrogate the injured state of tubule. The ratio of fibrosis aTECs and progenitor or proliferative aTECs in urine features tubular injury state and may help improve DKD diagnosis.
Authors
- Qin Zhou (ORCID: https://orcid.org/0000-0003-3879-4021)
- Dong-Zhao Ma (ORCID: https://orcid.org/0000-0002-4606-4339)
- Yagui Qiu (ORCID: https://orcid.org/0000-0003-0013-1484)
- Minghui Xu (ORCID: https://orcid.org/0000-0001-6738-6161)
- Wei Chen (ORCID: https://orcid.org/0000-0001-7196-8703)
- Jianbo Li (ORCID: https://orcid.org/0000-0001-7916-0944)
- Zhijian Li (ORCID: https://orcid.org/0000-0002-2308-7060)
- Jianwen Yu
- Naya Huang
- Ning Luo (ORCID: https://orcid.org/0000-0002-6616-2219)
- Jinjin Fan
- Yue Yang (ORCID: https://orcid.org/0000-0002-8270-9464)
- Dan Wang (ORCID: https://orcid.org/0000-0001-7789-6747)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Kidney International Reports
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1016/j.ekir.2024.11.002
- Citations
- 5
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Basic and Applied Basic Research Foundation of Guangdong Province