Changes in central venous-to-arterial PCO2 difference and central venous oxygen saturation as markers to define fluid responsiveness in critically ill patients: a pot-hoc analysis of a multi-center prospective study
In mechanically critically ill patients, ΔP(v-a)CO<sub>2</sub> and ΔScvO<sub>2</sub> are reliable parameters to define FR and can be used in the absence of CI measurement. The response to VE was independent of baseline ScvO<sub>2</sub> and P(v-a)CO<sub>2</sub> levels. Clinical trial registration The study was registered in the ClinicalTrials.gov registry: NCT03225378, date: July 20, 2017.
Authors
- Malcolm Lemyze (ORCID: https://orcid.org/0009-0000-1104-7777)
- Jihad Mallat (ORCID: https://orcid.org/0000-0001-6372-7360)
- Daniel Saleh (ORCID: https://orcid.org/0000-0003-4849-6933)
- Pierre‐Grégoire Guinot (ORCID: https://orcid.org/0000-0002-7019-9727)
- Osama Abou‐Arab (ORCID: https://orcid.org/0000-0003-3766-716X)
- Marc-Olivier Fischer
Institutions
- University of Arizona (US)
- Université de Bourgogne (FR)
- Cleveland Clinic Lerner College of Medicine (US)
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Abu Dhabi Health Services (AE)
- Centre Hospitalier de Lens (FR)
- CHU Dijon Bourgogne (FR)
- Centre Hospitalier d'Arras (FR)
- Centre de recherche Translationnelle en Médecine moléculaire (FR)
- Institut Polytechnique de Bordeaux (FR)
- Physiopathologie et Stratégies d'Imagerie du Remodelage cardiovasculaire
- Université de Picardie Jules Verne (FR)
- Université de Franche-Comté (FR)
Publication Details
- Journal
- Critical Care
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s13054-024-05156-y
- Citations
- 5
- Primary Topic
- Hemodynamic Monitoring and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.86