Anti-Sp4 and anti-CCAR1 autoantibodies in UK <i>vs</i> US patients with adult and juvenile-onset anti-TIF1γ-positive myositis
Anti-Sp4 and anti-CCAR1 autoantibodies are less common in the adult UK anti-TIF1γ-positive myositis population compared with published data from the USA, limiting their use as biomarkers for cancer risk. In patients with juvenile onset disease, anti-Sp4 is less frequent in UK patients compared with the USA, but the prevalence of anti-CCAR1 autoantibodies is similar.
Authors
- Claire T. Deakin (ORCID: https://orcid.org/0000-0002-7044-5801)
- Verna Cuthbert
- Muthana Al-Obadi
- Livia Casciola‐Rosen (ORCID: https://orcid.org/0000-0002-4172-1539)
- Elizabeth Stretton
- Amy Huffenberger
- Lee S. Nguyen (ORCID: https://orcid.org/0000-0002-6014-6269)
- Heather Chisem
- Hemlata Varsani
- Audrey Juggins
- Manija Asif
- Kiran Nistala
- Eileen Baildam (ORCID: https://orcid.org/0000-0001-8463-6388)
- Linda Suffield (ORCID: https://orcid.org/0000-0002-8306-9438)
- Jane Roach
- Anna Fry
- V. Stevenson
- Louise Turner (ORCID: https://orcid.org/0000-0003-4494-2289)
- Fionnuala K McMorrow
- Julie Cook
- Phil Riley
- Michael Browne (ORCID: https://orcid.org/0000-0003-3718-0087)
- Raquel Marques (ORCID: https://orcid.org/0000-0002-1445-7592)
- Neil A. Martin (ORCID: https://orcid.org/0000-0002-6565-4131)
- Chia-Ping Chou
- Emily Robinson
- Clarissa Pilkington (ORCID: https://orcid.org/0000-0003-2289-2428)
- Charalampia Papadopoulou (ORCID: https://orcid.org/0000-0002-1237-0557)
- Adaani Frost (ORCID: https://orcid.org/0000-0002-5566-2103)
- Jeanette Hall
- Lauren E. Stone (ORCID: https://orcid.org/0000-0003-1072-3133)
- Meredyth Wilkinson (ORCID: https://orcid.org/0000-0002-7972-8066)
- Polly Livermore (ORCID: https://orcid.org/0000-0003-0824-3878)
- Lorena Caruana
- Laura Kassoumeri
- Steven D. Leach (ORCID: https://orcid.org/0000-0002-2689-1871)
- Parichat Khaosut (ORCID: https://orcid.org/0000-0001-5343-3887)
- Alexander Oldroyd (ORCID: https://orcid.org/0000-0001-5701-6490)
- Emily Blyth (ORCID: https://orcid.org/0000-0002-7849-7139)
- Virginia Brown (ORCID: https://orcid.org/0000-0001-5961-9586)
- T. R. E. Southwood
- J Ioannou
- Andrew Lee Mammen (ORCID: https://orcid.org/0000-0003-3732-3252)
- Helen Foster (ORCID: https://orcid.org/0000-0003-0905-6142)
- Lucy R. Wedderburn (ORCID: https://orcid.org/0000-0002-7495-1429)
- Liz Waxman
- Heather Rostron (ORCID: https://orcid.org/0000-0001-8324-3451)
- Ruth Etherton
- Lisa G. Rider (ORCID: https://orcid.org/0000-0002-6912-2458)
- Laura Hennelly
- Giulia Varnier (ORCID: https://orcid.org/0000-0002-0261-5960)
- Ruth Howman
- Eve Smith (ORCID: https://orcid.org/0000-0002-8371-7597)
- Yvonne Glackin
- Hans de Graaf (ORCID: https://orcid.org/0000-0001-8055-8749)
- Sarah Hanson (ORCID: https://orcid.org/0000-0003-4751-8248)
- Christopher Piper (ORCID: https://orcid.org/0000-0001-6157-4612)
- E. J. MacLeod
- Margaret Connon
- Mary Jordan (ORCID: https://orcid.org/0000-0002-0497-8634)
- Ethan S Sen (ORCID: https://orcid.org/0000-0003-0135-6546)
- Stephen Crulley
- Stefanie Stafford
- Vanessa VanRooyen
- Danielle Miller
- Kathryn Bailey (ORCID: https://orcid.org/0000-0003-4525-8673)
- Mark Wood
- Kirsty Haslam
- Miss Caroline Miller
- Kevin Murray (ORCID: https://orcid.org/0000-0002-8856-6046)
- Socrates Varakliotis (ORCID: https://orcid.org/0000-0002-5265-8205)
- Lynne Bell (ORCID: https://orcid.org/0000-0003-0677-021X)
- Hector Chinoy (ORCID: https://orcid.org/0000-0001-6492-1288)
- Katie Arnold
- Sandrine Lacassagne
- Louise Akeroyd
- Louise Hanna (ORCID: https://orcid.org/0000-0001-8383-8164)
- Neil McHugh (ORCID: https://orcid.org/0000-0003-2765-658X)
- Stefanie Dowle
- Stephanie Simou
- Roisin Boyle
- Caitlin Clifford
- Sue A. Ferguson (ORCID: https://orcid.org/0000-0003-1193-2869)
- Mary A. Beard
- Helen Smith (ORCID: https://orcid.org/0000-0003-4308-9335)
- Dario Cancemi (ORCID: https://orcid.org/0000-0001-9343-6855)
- Janine A. Lamb (ORCID: https://orcid.org/0000-0002-7248-0539)
- Rosie Hamilton
- Rebecca Cutts
- Sarah Tansley (ORCID: https://orcid.org/0000-0003-4633-9598)
- Coziana Ciurtin (ORCID: https://orcid.org/0000-0002-8911-4113)
- H Venning
- Liza McCann (ORCID: https://orcid.org/0000-0002-0372-5758)
- Claire Duong
- Lindsay Crate
- Stuart Watson (ORCID: https://orcid.org/0000-0002-2558-3367)
- Melanie Marsh
- E. J. C. Kendall
- Olivia Lloyd
- Alice Leahy
- Natalie Fineman
- Flora McErlane (ORCID: https://orcid.org/0000-0002-2328-2122)
- Ellen Mosley
- Sue Maillard
- Sian Lunt
- Helen Pluess-Hall
- Liang Qiao (ORCID: https://orcid.org/0000-0002-9731-4166)
- Helen Lee (ORCID: https://orcid.org/0000-0002-1044-9843)
- Lucy Marshall (ORCID: https://orcid.org/0000-0003-3383-4274)
- Ann McGovern
- Satyapal Rangaraj
- Ian Roberts
- Clive Ryder
- Christina Boros
- Brian Davidson
- Kate Armon
- Michelle Andrews
- Amy Collier
- Susanne Cathcart
- Beverley Thomas
- Andrew J. Davies
- Mark Friswell
- Nathan Hasson
- Anne-Marie McMahon
- Andrew C. Swift
- Sue Wyatt
- Eslam Al-Abadi
- Gillian Jackson
- Josh Bennet
- Louise Coke
- Jacqui Clinch
- Janet Gardner‐Medwin
- Trudy Booth
- Douglas L. Mayers
- Debbie Wade
- Sunil Sampath (ORCID: https://orcid.org/0000-0001-5134-3036)
- Tania Amin
- Sharmila Jandial
- Sally A. Smith
- Nick Wilkinson
- Beverley Almeida
- J Scott
- Deborah Burton
- Kishore Warrier
- Shireena A. Yasin
- Kathryn O’Brien
- Amy Nichols
- Cerise Johnson-Moore
- Dominic Igbelina
- Emma Inness
- Suzanne Sketchley
- Maisy Dawkins-Lloyd
- Lindsay Vallance
- Charlene Bass-Woodcock
- Sarah Hartfree
- Elizabeth Fofana
- Susan Wadeson
- Brogan Wrest
- Elizabeth Halkon
- Elli Enayat
- Paul Pryce
- Sharon King
Institutions
- Royal National Hospital for Rheumatic Diseases (GB)
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Manchester Academic Health Science Centre (GB)
- Johns Hopkins Medicine (US)
- Great Ormond Street Hospital (GB)
- University of Manchester (GB)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- National Institute of Environmental Health Sciences (US)
- National Institute of Nursing Research (US)
- Salford Royal Hospital (GB)
- Arthritis UK (GB)
- Institute of Child Health (IN)
- University College London (GB)
- University of Bath (GB)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1093/rheumatology/keae574
- Citations
- 2
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Wellcome Trust
- University Hospital Southampton NHS Foundation Trust
- Myositis Association
- Action Medical Research
- National Institute for Health and Care Research
- Department of Health and Social Care
- University College London
- University of Oxford
- Deakin University
- Hospital for Sick Children
- Versus Arthritis
- National Institutes of Health
- Manchester Biomedical Research Centre
- Medical Research Council