<i>BRAF</i> Deletion in Adult Patients with Langerhans Cell Histiocytosis Correlates with Multisystem Disease and Poor Outcomes
This large study provides molecular and clinical pathologic characterization of adult LCH. BRAFindel was highly correlated with MS LCH and was associated with worse outcomes.
Authors
- Minghui Duan (ORCID: https://orcid.org/0000-0003-2130-6300)
- Min Lang (ORCID: https://orcid.org/0009-0000-5381-5850)
- Daobin Zhou (ORCID: https://orcid.org/0000-0002-1592-1932)
- Xinxin Cao (ORCID: https://orcid.org/0000-0001-7884-3073)
- Hao Cai (ORCID: https://orcid.org/0000-0003-2153-9470)
- Zheng-zheng Liu
- He Lin
- Long Chang (ORCID: https://orcid.org/0000-0002-1026-016X)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-1802
- Citations
- 4
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- National Key Research and Development Program of China