Transcriptomics of Subcutaneous Tissue of Lipedema Identified Differentially Expressed Genes Involved in Adipogenesis, Inflammation, and Pain
In summary, the pathogenesis and development of lipedema might be caused by alterations in adipogenesis, inflammation, and extracellular matrix remodeling, leading to fibrosis and the formation of edema resulting in this painful disease. These processes differ from hypertrophied adipose tissue and may therefore play a main role in the formation of lipedema.
Authors
- I. Meier-Vollrath
- Matthias Brandenburger
- Axel Baumgartner (ORCID: https://orcid.org/0000-0002-0365-8591)
- Tobias Kisch (ORCID: https://orcid.org/0000-0002-0655-2119)
- Yvonne Frambach
- Maria Karolin Streubel (ORCID: https://orcid.org/0000-0001-8708-3635)
Institutions
- University Hospital Schleswig-Holstein (DE)
- Fraunhofer-Einrichtung für Individualisierte Medizintechnik (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Plastic & Reconstructive Surgery Global Open
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1097/gox.0000000000006288
- Citations
- 12
- Primary Topic
- Hereditary Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.22