Targeting c-MET for Endoscopic Detection of Dysplastic Lesions within Barrett’s Esophagus Using EMI-137 Fluorescence Imaging
EMI-137 accumulates in dysplastic lesions within Barrett's esophagus and also in c-MET-positive esophageal adenocarcinoma. EMI-137 imaging has potential as a screening and surveillance tool for patients with Barrett's esophagus and as a means to detecting dysplasia and esophageal adenocarcinoma.
Authors
- Yi‐Jhih Huang (ORCID: https://orcid.org/0000-0002-5931-8975)
- Kel Vin Tan (ORCID: https://orcid.org/0000-0002-5762-6958)
- Jonas Rieder
- Dimitris Gorpas (ORCID: https://orcid.org/0000-0001-9576-8087)
- Michael Quante (ORCID: https://orcid.org/0000-0002-8497-582X)
- Borivoj Vojnovic (ORCID: https://orcid.org/0000-0001-9013-3816)
- Katherine A. Vallis (ORCID: https://orcid.org/0000-0003-4672-5683)
- Anna Tenditnaya (ORCID: https://orcid.org/0000-0002-8421-4991)
Institutions
- University of Freiburg (DE)
- Royal Institute of Navigation (GB)
- University Medical Center Freiburg (DE)
- Helmholtz Zentrum München (DE)
- University of Oxford (GB)
- Invicro (United Kingdom) (GB)
- Science Oxford (GB)
- Technical University of Munich (DE)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-1522
- Citations
- 2
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Cancer Research UK
- Deutsche Forschungsgemeinschaft
- Albert-Ludwigs-Universität Freiburg
- Medical Affairs Bureau
- Medizinische Fakultät der Albert-Ludwigs-Universität Freiburg