Depression revealing Fahr's syndrome in association with primary autoimmune hypoparathyroidism: A case report

Fahr’s syndrome is a rare entity characterised by the presence of intracerebral calcifications, which are mainly located in the basal ganglia, and are bilateral and symmetrical. It is associated with phosphocalcium metabolism disorders, such as hypoparathyroidism. It can manifest as a variety of neurological or psychiatric disorders. We report the case of a 60-year-old female patient with primary autoimmune hypoparathyroidism, who presented with a depressive syndrome. Paraclinical investigations indicated the presence of Fahr’s syndrome, which was associated with chronic hypocalcemia due to digestive malabsorption, and aggravated by therapeutic non-adherence due to her depression.