Predictors of trigeminal neuropathy in patients receiving Gamma Knife stereotactic radiosurgery for vestibular schwannoma

The only significant factor in the risk of development of Tn after SRS for VS was the volume of CN V that received ≥ 11 Gy. This should be routinely incorporated into dosimetric planning constraints and patients should be counseled about the risk of adverse effects if it cannot be met. For those with growing VS and a gap to the trigeminal nerve, it may be prudent to provide earlier treatment with SRS to enable application of this dosimetric constraint and reduced risk of Tn.

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Publication Details

Journal
Journal of neurosurgery
Published
2024-11-01
DOI
https://doi.org/10.3171/2024.7.jns24538
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Predictors of trigeminal neuropathy in patients receiving Gamma Knife stereotactic radiosurgery for vestibular schwannoma

Philip J. Clamp, Louise Wade, William Brown, Alison Cameron et al.
Journal of neurosurgery
Meningioma and schwannoma management
article

Predictors of trigeminal neuropathy in patients receiving Gamma Knife stereotactic radiosurgery for vestibular schwannoma

Philip J. Clamp, Louise Wade, William Brown, Alison Cameron, H. Worth Boyce
article en

Abstract

The only significant factor in the risk of development of Tn after SRS for VS was the volume of CN V that received ≥ 11 Gy. This should be routinely incorporated into dosimetric planning constraints and patients should be counseled about the risk of adverse effects if it cannot be met. For those with growing VS and a gap to the trigeminal nerve, it may be prudent to provide earlier treatment with SRS to enable application of this dosimetric constraint and reduced risk of Tn.

Journal of neurosurgeryVol. 142(4)
University Hospitals Bristol NHS Foundation Trust (GB), Southmead Hospital (GB), Royal United Hospital Bath NHS Trust (GB), University Hospitals Bristol and Weston NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 70%
Meningioma and schwannoma management
DOISourceOpenAlex
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Predictors of trigeminal neuropathy in patients receiving Gamma Knife stereotactic radiosurgery for vestibular schwannoma — Philip J. Clamp, Louise Wade, et al. · Journal of neurosurgery (2024) | TGRS Research Map | TGRS