[<i>HNRNPA1</i> gene is highly expressed in colorectal cancer: its prognostic implications and potential as a therapeutic target].
HNRNP A1 is overexpressed in CRC tissues to modulate cell proliferation and migration and is correlated with a poorer prognosis. VPC-80051 can effectively inhibit CRC cell proliferation, suggesting the potential of HNRNP A1 as a therapeutic target for CRC.
Authors
- Le Zhou (ORCID: https://orcid.org/0000-0002-7852-1370)
- Kai Ji (ORCID: https://orcid.org/0000-0002-4040-0880)
- Bo Zhu (ORCID: https://orcid.org/0000-0002-5708-8459)
- Wanrong Man
- Tong Zhang (ORCID: https://orcid.org/0000-0002-8151-3697)
- Qing Ling (ORCID: https://orcid.org/0000-0002-6670-2473)
- Guan Yu Yu
- Wancong Zhang
Institutions
- Bengbu Medical College (CN)
- Second Military Medical University (CN)
- Changhai Hospital (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-09-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.09.08
- Primary Topic
- Mechanisms of cancer metastasis
- Type
- article