[Reoxygenation improves reduced hypothalamic leptin responsiveness induced by intermittent hypoxia in obese rats].
Prolonged intermittent hypoxia impairs hypothalamic leptin signaling by downregulating LepR expression to promote weight gain in obese rats, which can be improved by reoxygenation treatment.
Authors
- Maolong Dong (ORCID: https://orcid.org/0000-0002-2539-5438)
- Yingqing Feng (ORCID: https://orcid.org/0000-0003-0443-5506)
- Teng Zhu (ORCID: https://orcid.org/0000-0002-1754-4878)
- Xuan Du (ORCID: https://orcid.org/0000-0003-4584-7400)
- W. F. Mader (ORCID: https://orcid.org/0000-0002-7344-998X)
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-09-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.09.09
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
Funders
- National Natural Science Foundation of China