[Isongifolene Improves Crohn's Disease-Like Colitis in Mice by Reducing Apoptosis of Intestinal Epithelial Cells].
ISO reduces intestinal epithelial cell apoptosis at least in part by activating AMPK/PGC1α signaling pathway, thereby alleviating TNBS-induced intestinal barrier dysfunction and CD-like colitis in mice.
Authors
- Jing Li (ORCID: https://orcid.org/0000-0003-2474-9027)
- Zhijun Geng (ORCID: https://orcid.org/0000-0002-4040-5622)
- Jianguo Hu
- Mingxi Sun
- Guoyu Lu
- Shunyin Wang
- Lixia Yin (ORCID: https://orcid.org/0009-0005-6852-5713)
- Jingjing Yang (ORCID: https://orcid.org/0000-0003-2579-3919)
- Xiaofeng Zhang (ORCID: https://orcid.org/0000-0003-2738-3286)
- Ting Duan (ORCID: https://orcid.org/0000-0003-0575-5675)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-09-20
- DOI
- https://doi.org/10.12182/20240960204
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article