Surface-functionalized UIO-66-NH2 for dual-drug delivery of vancomycin and amikacin against vancomycin-resistant Staphylococcus aureus
These findings highlighted the efficiency of VAN/AMK-UIO-66@NH<sub>2</sub>/PEG in combating antimicrobial resistance and biofilm formation in VRSA isolates. Future studies, particularly in vivo models, are necessary to evaluate the safety, efficacy, and clinical applicability of these nanoparticles for the treatment of bacterial infections.
Authors
- Aram Sharifi (ORCID: https://orcid.org/0000-0002-1416-9726)
- Sepideh Asadi (ORCID: https://orcid.org/0000-0002-3659-6745)
- Fatemeh Ashrafi (ORCID: https://orcid.org/0000-0003-0369-2092)
- Nazanin Rahmanian (ORCID: https://orcid.org/0000-0001-9591-1795)
- Pooria Moulavi (ORCID: https://orcid.org/0000-0001-8010-3023)
Institutions
- Islamic Azad University North Tehran Branch (IR)
- University of Tehran (IR)
- Islamic Azad University Medical Branch of Tehran (IR)
- University of Kurdistan (IR)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1186/s12866-024-03615-8
- Citations
- 17
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 6.61
Funders
- Islamic Azad University