Dirhodium-Catalyzed [2 + 2 + 2] Cycloaddition of 1,6-Diynes and Alkynes
A facile method for the construction of fused arenes has been developed through dirhodium-catalyzed [2 + 2 + 2] cycloaddition, which represents a new application of dirhodium complexes. This protocol is convenient to handle without the addition of extra ligands and reductants and tolerates a broad range of functional groups. Mechanistic studies revealed that the two-electron oxidation process, carboxylate ligand departure, and heteroatom coordination-promoted [2 + 2 + 2] cycloaddition were possibly involved.
Authors
- Shifa Zhu (ORCID: https://orcid.org/0000-0001-5172-7152)
- Rui Wu (ORCID: https://orcid.org/0009-0004-0054-6553)
- Wendeng Li
- Xiang Gao (ORCID: https://orcid.org/0000-0002-1732-2132)
- Yang Chen (ORCID: https://orcid.org/0000-0003-3365-8805)
Institutions
- Zhejiang Sci-Tech University (CN)
- South China University of Technology (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-11-08
- DOI
- https://doi.org/10.1021/acs.joc.4c01780
- Citations
- 4
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.00
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project
- Fundamental Research Funds for the Central Universities
- Basic and Applied Basic Research Foundation of Guangdong Province