Effects of COVID-19 on bone fragility: a new perspective from osteoimmunological biomarkers
Taken together these results indicate that the use of an osteoimmunological biomarker like the RANKL/OPG ratio could provide a significant improvement in the clinical evaluation of the COVID-19 effect on bone loss. This aspect is extremely important in elderly patients undergoing orthopedic surgery, which can manifest more severe effects of COVID-19 and present an increased level of age-induced bone fragility.
Authors
- Giuseppe Maria Peretti (ORCID: https://orcid.org/0000-0001-9341-7187)
- Luca Massaccesi (ORCID: https://orcid.org/0000-0002-2690-7095)
- Massimiliano Marco Corsi Romanelli (ORCID: https://orcid.org/0000-0001-7928-7697)
- Emanuela Galliera (ORCID: https://orcid.org/0000-0002-0764-3178)
- Laura Mangiavini (ORCID: https://orcid.org/0000-0003-1892-1249)
- Elena De Vecchi (ORCID: https://orcid.org/0000-0001-9781-8607)
- Francesca Villa
Institutions
- University of Milan (IT)
- IRCCS Ospedale Galeazzi - Sant'Ambrogio (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fimmu.2024.1493643
- Citations
- 4
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- Università degli Studi di Milano
- Ministero della Salute