Development of pituitary dysfunction and destructive thyroiditis is associated with better survival in non-small cell lung cancer patients treated with programmed cell death-1 inhibitors: a prospective study with immortal time bias correction
NSCLC patients developing pituitary dysfunction and destructive thyroiditis showed better OS even after adjusting for ITB, suggesting that these irAEs indicate a better prognosis.
Authors
- Tetsushi Izuchi
- Mariko Sugiyama (ORCID: https://orcid.org/0000-0001-6289-1249)
- Koki Otake
- Koji Suzuki (ORCID: https://orcid.org/0000-0002-3235-9558)
- Shintaro Iwama (ORCID: https://orcid.org/0000-0002-3281-0337)
- Makoto Ishii (ORCID: https://orcid.org/0000-0003-4396-1664)
- Tetsunari Hase (ORCID: https://orcid.org/0000-0002-9653-8424)
- Ryoichi Banno (ORCID: https://orcid.org/0000-0002-8546-1636)
- Hidetaka Suga (ORCID: https://orcid.org/0000-0003-1924-7639)
- Hiroshi Arima (ORCID: https://orcid.org/0000-0003-3746-1997)
- Takeshi Onoue (ORCID: https://orcid.org/0000-0002-8589-9937)
- Masahiko Ando (ORCID: https://orcid.org/0000-0003-2891-5424)
- Tomoko Handa (ORCID: https://orcid.org/0000-0003-3729-9512)
- Megumi Inoue (ORCID: https://orcid.org/0000-0001-8077-6711)
- Tomoko Kobayashi (ORCID: https://orcid.org/0000-0002-4251-4865)
- Takashi Miyata (ORCID: https://orcid.org/0000-0002-1479-2251)
- Daisuke Hagiwara (ORCID: https://orcid.org/0000-0002-4353-231X)
Institutions
- Nagoya University Hospital (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fendo.2024.1490042
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.57