Pro-inflammatory macrophages suppress HIV replication in humanized mice and ex vivo co-cultures
This study describes a novel role of macrophages as effector cells, both <i>ex vivo</i> and <i>in vivo</i>, acting against HIV replication and limiting disease progression.
Authors
- Christina K. S. Muller
- Tafadzwa Mlambo
- Simon Bredl (ORCID: https://orcid.org/0000-0001-6822-755X)
- Nicole P. Kadzioch (ORCID: https://orcid.org/0000-0002-0432-8658)
- Doris Russenberger
- Roberto F. Speck (ORCID: https://orcid.org/0000-0002-8453-1137)
- Rebekka Wolfensberger (ORCID: https://orcid.org/0000-0003-3782-9691)
- Luca Baroncini
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fimmu.2024.1439328
- Citations
- 3
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Eidgenössische Technische Hochschule Zürich
- Universität Zürich
- Swiss Vaccine Research Institute
- Functional Genomics Center Zurich