AKK-derived outer membrane vesicles alleviate indomethacin-induced mucin secretion reduction in LS174T cells by inhibiting endoplasmic reticulum stress
AKK-OMVs can directly stimulate goblet cells to promote MUC2 secretion, providing potential for further <i>in vivo</i> studies to confirm their protective effects against indomethacin-induced intestinal injury.
Authors
- Huixi Liang
- Xin Chen (ORCID: https://orcid.org/0000-0001-7706-4166)
- Jingwen Zhao (ORCID: https://orcid.org/0009-0002-6913-5838)
- Shuang Ma (ORCID: https://orcid.org/0009-0008-4569-6159)
- Lijun Zhang (ORCID: https://orcid.org/0000-0003-4974-2745)
Institutions
- Tianjin Medical University General Hospital (CN)
- Tianjin Infectious Diseases Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fmolb.2024.1418876
- Citations
- 1
- Primary Topic
- Adenosine and Purinergic Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.40