Banxia-Yiyiren alleviates insomnia and anxiety by regulating the gut microbiota and metabolites of PCPA-induced insomnia model rats
This study preliminarily verified that the PCPA-induced insomnia model is closely related to gut microbial metabolism and microecological disorders, and for the first time, we confirmed that Banxia-Yiyiren can act on the gut microbiota of PCPA-induced insomnia model rats and alleviate insomnia and anxiety by regulating the species, structure, abundance, and metabolites of the gut microbiota.
Authors
- Yingfan Chen
- Shaodan Li (ORCID: https://orcid.org/0000-0001-5908-4999)
- Ningli Chai (ORCID: https://orcid.org/0000-0003-0583-4189)
- Xiaorong Qi (ORCID: https://orcid.org/0000-0002-8382-9433)
- Qi Chen (ORCID: https://orcid.org/0000-0002-1959-1854)
- Tao Zou (ORCID: https://orcid.org/0000-0003-2177-9490)
- Shuo Wang (ORCID: https://orcid.org/0000-0002-3146-5818)
- Liang Wang (ORCID: https://orcid.org/0000-0001-5339-7484)
- Zihan Liu (ORCID: https://orcid.org/0009-0000-4573-9368)
- Yunshan Zhao
- Chujiao Tian
- Minghui Yang
Institutions
- Chinese PLA General Hospital (CN)
- 82th Hospital of Pla (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fmicb.2024.1405566
- Citations
- 5
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.17