Investigating neural markers of Alzheimer's disease in posttraumatic stress disorder using machine learning algorithms and magnetic resonance imaging
Results suggest that patients with PTSD with reduced GM volume in the right temporal regions (parahippocampal gyrus) experienced greater symptom severity and showed more AD-like brain activity. These results show potential for early identification of those who may be at an increased risk for future development of dementia.
Authors
- Lawrence Ryner
- Ji Hyun Ko (ORCID: https://orcid.org/0000-0002-9700-7692)
- Tiffany A. Kolesar (ORCID: https://orcid.org/0000-0003-0186-5324)
- Natalie Wright (ORCID: https://orcid.org/0000-0003-3893-029X)
- Sarah J. Chaulk
- Iman Beheshti (ORCID: https://orcid.org/0000-0003-4750-3433)
- Eun Hyung Choi
- Ronak Patel (ORCID: https://orcid.org/0000-0003-1255-5903)
- Gabriella Yakemow
Institutions
- Health Sciences Centre (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fneur.2024.1470727
- Citations
- 4
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Workers Compensation Board of Manitoba
- Natural Sciences and Engineering Research Council of Canada