Non‐occlusive mesenteric ischemia developing post‐chemotherapy for oral squamous cell carcinoma: A case report and literature review

Abstract Background Non‐occlusive mesenteric ischemia (NOMI) is a rare, symptom‐scarce condition characterized by rapid progression and high mortality. Case presentation A 63‐year‐old male, after recovering from neutropenia following paclitaxel and cetuximab therapy, developed abdominal distension without subjective symptoms. Dynamic CT imaging suggested ischemia in the superior mesenteric artery region without vascular obstruction, leading to a diagnosis of NOMI. With no clear signs of intestinal necrosis, conservative treatment was chosen, but the patient succumbed within 14 h. Conclusion Cancer chemotherapy agents may induce intestinal ischemia. Stomatologists should be aware of this disease and facilitate timely referral to specialists for appropriate medical care.

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Publication Details

Journal
Oral Science International
Published
2024-11-06
DOI
https://doi.org/10.1002/osi2.1280
Primary Topic
Abdominal vascular conditions and treatments
Type
article
Field-Weighted Citation Impact
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article

Non‐occlusive mesenteric ischemia developing post‐chemotherapy for oral squamous cell carcinoma: A case report and literature review

Shoya Ono, Kumiko Hatsukawa, Akio Shibata, Kou Kawahara et al.
Oral Science International
Abdominal vascular conditions and treatments
article

Non‐occlusive mesenteric ischemia developing post‐chemotherapy for oral squamous cell carcinoma: A case report and literature review

Shoya Ono, Kumiko Hatsukawa, Akio Shibata, Kou Kawahara, Yuki Tange, Ryosuke Ogikubo
article en

Abstract

Abstract Background Non‐occlusive mesenteric ischemia (NOMI) is a rare, symptom‐scarce condition characterized by rapid progression and high mortality. Case presentation A 63‐year‐old male, after recovering from neutropenia following paclitaxel and cetuximab therapy, developed abdominal distension without subjective symptoms. Dynamic CT imaging suggested ischemia in the superior mesenteric artery region without vascular obstruction, leading to a diagnosis of NOMI. With no clear signs of intestinal necrosis, conservative treatment was chosen, but the patient succumbed within 14 h. Conclusion Cancer chemotherapy agents may induce intestinal ischemia. Stomatologists should be aware of this disease and facilitate timely referral to specialists for appropriate medical care.

Oral Science InternationalVol. 22(1)
Gifu Prefectural Tajimi Hospital (JP)
Good health and well-being
Openalex Percentile: Top 62%
Abdominal vascular conditions and treatments
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