Spleen tyrosine kinase inhibition mitigates radiation-induced lung injury through anti-inflammatory effects and downregulation of p38 MAPK and p53
Syk inhibitor may have a potential to be used as a targeted drug to mitigate radiation pneumonitis and inhibit radiation-induced pulmonary fibrosis.
Authors
- Guo‐Xing Zhang (ORCID: https://orcid.org/0000-0003-0647-4699)
- Xiaohua Li (ORCID: https://orcid.org/0000-0003-3490-916X)
- Ni Sun
Institutions
- Jilin University (CN)
- Jilin Province Tumor Hospital (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.3389/fonc.2024.1406759
- Citations
- 2
- Primary Topic
- Effects of Radiation Exposure
- Type
- article
- Field-Weighted Citation Impact
- 0.81