Clinical and Laboratory Characteristics of Pediatric Patients With <i>ACKR1/DARC</i>‐Associated Neutropenia
We identified ADAN in individuals of variable ethnicities, almost half with severe neutropenia. We recommend testing for ADAN in all children with isolated neutropenia without severe infections. Homozygosity for the ACKR1/DARC rs2814778 SNP may obviate the need for further investigation, follow-up, or treatment in specific clinical scenarios.
Authors
- lital Oz Alcalay (ORCID: https://orcid.org/0000-0002-1986-4146)
- Orly Dgany
- Oded Gilad (ORCID: https://orcid.org/0000-0002-0033-3425)
- Orna Steinberg‐Shemer (ORCID: https://orcid.org/0000-0002-1680-2388)
- Tanya Krasnov
- Eyal Elron (ORCID: https://orcid.org/0000-0002-5144-4993)
- Michal Dvori
- Sharon Noy‐Lotan (ORCID: https://orcid.org/0009-0001-0986-3641)
- Joanne Yacobovich (ORCID: https://orcid.org/0000-0003-3763-5694)
- Sarah Elitzur (ORCID: https://orcid.org/0000-0002-3495-7578)
- Hannah Tamary (ORCID: https://orcid.org/0000-0003-4745-3448)
- Dafna Brik‐Simon
Institutions
- Tel Aviv University (IL)
- Rabin Medical Center (IL)
- Schneider Children's Medical Center (IL)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2024-11-06
- DOI
- https://doi.org/10.1002/pbc.31430
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00