Empiric antibiotic prescribing practices for gram-positive coverage of late-onset sepsis in neonatal intensive care units in North America

Late-onset sepsis (LOS) in the neonatal intensive care unit (NICU) causes significant morbidity and mortality, yet guidance on empiric management is limited. We surveyed NICUs across Canada and the United States regarding their empiric antimicrobial regimens for LOS, thereby identifying large practice variations and high rates of empiric vancomycin use.

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Publication Details

Journal
Infection Control and Hospital Epidemiology
Published
2024-11-07
DOI
https://doi.org/10.1017/ice.2024.176
Citations
4
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
2.17
Controls
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article

Empiric antibiotic prescribing practices for gram-positive coverage of late-onset sepsis in neonatal intensive care units in North America

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4 citations
Infection Control and Hospital Epidemiology
Neonatal and Maternal Infections
2.17
article

Empiric antibiotic prescribing practices for gram-positive coverage of late-onset sepsis in neonatal intensive care units in North America

Kathryn Timberlake, Sandra Isabel, Sarah Khan, Pablo J. Sánchez, Michelle Science, David Kaufman, Dara Petel, Joseph Ting, Jim Wright, Kyong‐Soon Lee
article en
4 citations

Abstract

Late-onset sepsis (LOS) in the neonatal intensive care unit (NICU) causes significant morbidity and mortality, yet guidance on empiric management is limited. We surveyed NICUs across Canada and the United States regarding their empiric antimicrobial regimens for LOS, thereby identifying large practice variations and high rates of empiric vancomycin use.

Infection Control and Hospital EpidemiologyVol. 46(1)
Nationwide Children's Hospital (US), University of Alberta (CA), Hospital for Sick Children (CA), Public Health Ontario (CA), Université Laval (CA), University of Virginia (US), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 12%
Neonatal and Maternal Infections
2.17
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