lncRNA LINC02323 predicts adverse neoadjuvant chemotherapy outcomes of gastric cancer patients and regulates cell sensitivity to 5-fluorouracil by negatively modulating miR-139-3p
Upregulated LINC02323 expression in gastric cancer is associated with malignant progression, adverse prognosis, and chemotherapy resistance. Silencing LINC02323 could enhance the sensitivity of gastric cancer cells to 5-FU by negatively modulating miR-139-3p expression.
Authors
- Zexu Chen (ORCID: https://orcid.org/0000-0002-6054-7898)
- Zhaoguang Wang (ORCID: https://orcid.org/0000-0002-3939-2625)
- Haihan Zhang (ORCID: https://orcid.org/0000-0002-2770-0627)
- Xiaodong Zhang (ORCID: https://orcid.org/0000-0003-4000-4180)
- Zhentao Li (ORCID: https://orcid.org/0000-0001-9744-9944)
Institutions
- Xuzhou Medical College (CN)
- Jiangsu Province Hospital (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1080/07853890.2024.2424513
- Citations
- 7
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 2.00