Quantitative Assessment of Collagen Architecture to Determine Role of Tumor Stroma During Vestibular Schwannoma Progression
Larger VS exhibit increased collagen abundance in the tumor stroma, and a more disorganized collagen architecture compared to smaller VS and normal peripheral nerve tissue. This finding indicates that collagen organization may play a significant role in extracellular matrix remodeling and the progression of VS.
Authors
- Kyle Wu (ORCID: https://orcid.org/0000-0003-0009-5049)
- Han T. N. Nguyen
- Bailey H. Duhon (ORCID: https://orcid.org/0000-0002-4355-6565)
- Jeffrey R. Tonniges (ORCID: https://orcid.org/0000-0001-7625-8874)
- Melanie Fisher (ORCID: https://orcid.org/0000-0001-6659-9421)
- Yin Ren (ORCID: https://orcid.org/0000-0002-3865-0012)
Institutions
- The Ohio State University Wexner Medical Center (US)
- The Ohio State University (US)
Publication Details
- Journal
- Otolaryngology
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1002/ohn.1018
- Citations
- 1
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Ohio State University
- National Cancer Institute
- National Institute on Deafness and Other Communication Disorders