Transcriptome analysis identifies the NR4A subfamily involved in the alleviating effect of folic acid on mastitis induced by high concentration of Staphylococcus aureus lipoteichoic acid
Our study revealed that low and high concentrations of aLTA have opposite effects on apoptosis and necrosis of Mac-T and that FA can alleviate the apoptosis induced by high concentration of aLTA. Transcriptome analysis revealed that the NR4A subfamily play a role in the ability of FA to alleviate the apoptosis and necrosis induced by high concentration of aLTA.
Authors
- Ying Yu (ORCID: https://orcid.org/0000-0002-4524-0791)
- Siyuan Mi (ORCID: https://orcid.org/0000-0003-4950-689X)
- Quanzhen Chen (ORCID: https://orcid.org/0000-0002-7481-9997)
- Yongjie Tang (ORCID: https://orcid.org/0000-0002-3298-9023)
- Siqian Chen (ORCID: https://orcid.org/0000-0001-8358-8732)
- Yue Xing (ORCID: https://orcid.org/0000-0002-9642-8540)
- Songyan An (ORCID: https://orcid.org/0009-0005-0172-6633)
- Yajing Wang (ORCID: https://orcid.org/0000-0002-3605-8437)
Institutions
- Ministry of Agriculture (ID)
- China Agricultural University (CN)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12864-024-10895-x
- Citations
- 2
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China
- Earmarked Fund for Modern Agro-industry Technology Research System
- National Key Research and Development Program of China