Hypermethioninemia due to methionine adenosyltransferase I/III deficiency and brain damage
Methionine adenosyltransferase I/III deficiency is not just a benign disease. Severe persistent hypermethioninemia can cause brain injuries, especially in the white matter. Liver transplantation may be a potential treatment option for refractory methionine adenosyltransferase I/III deficiency.
Authors
- Zhi‐Jun Zhu (ORCID: https://orcid.org/0000-0001-7031-2083)
- Ruxuan He (ORCID: https://orcid.org/0000-0002-5685-9194)
- Zhehui Chen (ORCID: https://orcid.org/0000-0002-6139-5347)
- Huiting Zhang
- Mei Lu (ORCID: https://orcid.org/0000-0002-8709-7567)
- Li‐Ying Sun
- Yi Liu (ORCID: https://orcid.org/0000-0003-4030-9670)
- Yao Zhang (ORCID: https://orcid.org/0000-0003-3408-3556)
- Xue Ma (ORCID: https://orcid.org/0009-0008-2012-2140)
- Yanling Yang (ORCID: https://orcid.org/0000-0002-1566-6441)
- Mengqiu Li
- Yongxing Chen (ORCID: https://orcid.org/0000-0002-4131-137X)
- Hui Dong (ORCID: https://orcid.org/0000-0002-8463-2413)
- Lulu Kang (ORCID: https://orcid.org/0009-0001-9342-0498)
- Ying Jin (ORCID: https://orcid.org/0000-0002-0866-1634)
- Jinqing Song
Institutions
- Capital Medical University (CN)
- Xiamen University (CN)
- Peking University (CN)
- China-Japan Friendship Hospital (CN)
- Zhengzhou Children's Hospital (CN)
- Peking University First Hospital (CN)
- Beijing Children’s Hospital (CN)
- Beijing Friendship Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2024-11-07
- DOI
- https://doi.org/10.1186/s12887-024-05196-x
- Citations
- 1
- Primary Topic
- Metabolism and Genetic Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.38
Funders
- National Key Research and Development Program of China