N6-methyladenosine regulators in hepatocellular carcinoma: investigating the precise definition and clinical applications of biomarkers

Our findings suggest that the mutual validation of big data analysis and functional experiments may facilitate the precise identification and definition of biomarkers, and our m6A risk models may have the potential to guide personalized chemotherapy, targeted treatment, and immunotherapy decisions in HCC.

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Publication Details

Journal
Biology Direct
Published
2024-11-07
DOI
https://doi.org/10.1186/s13062-024-00554-2
Citations
2
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.47

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article

N6-methyladenosine regulators in hepatocellular carcinoma: investigating the precise definition and clinical applications of biomarkers

Lulu Yin, Xinyue Yao, Guoqiang Wan, Jie Ying Fu et al.
2 citations
Biology Direct
RNA modifications and cancer
0.47
article

N6-methyladenosine regulators in hepatocellular carcinoma: investigating the precise definition and clinical applications of biomarkers

Lulu Yin, Xinyue Yao, Guoqiang Wan, Jie Ying Fu, Xiao Liu, Nanjing Zhou, Hao Wang, Yao Qi, Yingchun Gao, Xinxin Ye, Xiaokai Yan, Xing Chen
article en
2 citations

Abstract

Our findings suggest that the mutual validation of big data analysis and functional experiments may facilitate the precise identification and definition of biomarkers, and our m6A risk models may have the potential to guide personalized chemotherapy, targeted treatment, and immunotherapy decisions in HCC.

Biology DirectVol. 19(1)
Zunyi Medical University (CN), Zhejiang Cancer Hospital (CN), National Engineering Research Center for Nanotechnology (CN)
Natural Science Foundation of Guizhou Province, Natural Science Foundation of Zhejiang Province
Good health and well-being
Openalex Percentile: Top 34%
RNA modifications and cancer
0.47
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